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Address : 100 Tradecenter Dr, Suite 510 , Woburn, MA,01801
Spear Bio is building out its commercial and technical teams to help bring our solutions to market. To that end, we are looking for top talent with clinical diagnostics industry experience and functional experiences including R&D, Product Development, Business Development, and Product Management.
We offer a competitive compensation, with meaningful stock ownership, strong benefits, and a great work environment. This is an opportunity to enter a high-growth startup company at an early stage. We are recruiting candidates who have demonstrated leadership and excellence throughout their careers and are excited by the prospect of- and the effort involved in- building an industry-leading company.
Spear Bio Inc. provides equal opportunity in employment to everyone. No person shall be denied equal access because of race, creed, color, religion, national origin, sex, sexual orientation, gender identity, age, or physical/mental disability.
See Available Positions Below.
Scientist/Sr. Scientist
| Job Description
We are seeking a Scientist/Senior Scientist-level candidate with a track record of research excellence and diagnostic product development experience to join our R&D team. Expertise and knowledge of recent scientific and technological advances in molecular diagnostics and immunodiagnostics are required. The ideal candidate will be a highly motivated individual who leads from the bench and enjoys having broad responsibilities and opportunities. Activities may be focused on individual projects or assignments as a senior technical member of a project team, which may include project leadership duties.
| Requirements
Role-Specific Requirements
- Ph.D. in Molecular Biology, Biochemistry, Biomedical Engineering, or related field
- Extensive experience in PCR-based nucleic acid detection techniques (e.g., qRT-PCR, digital PCR).
- Experience with protein labeling and/or conjugation biochemistry is a plus.
- Experience in working with digital immunoassays platforms is a plus.
- Experience in diagnostic development for protein markers is a plus.
- Experience in automated liquid handling is a plus.
- Prior experience in working with various human biofluids is a plus.
- Experience in developing, implementing and supporting clinical assays in a regulated environment (such as with FDA-QSR, CLIA, ISO regulations) strongly preferred.
- Knowledge of the diagnostic industry is required; some knowledge of liquid biopsies is a plus.
- For the senior scientist level, 3+ years of professional experience with molecular biology techniques in an industry setting.
General requirements
- Strong analytical and problem-solving skills.
- Ability to maintain sustained attention to detail.
- Strong communication skills: interpersonal (verbal), writing, and via presentations.
- Ability to convey information in a clear and concise manner.
- Demonstrated ability to work collaboratively and in teams.
- Ability to travel within the United States.
| Responsibilities
- Develops, plans, conducts and records results from complex experiments within a specific product or technology area.
- Contributes ideas for new product development
- Performs laboratory experiments following defined protocols and company procedures, or innovates to develop new protocols for existing or new technologies.
- Reports on the status of assigned projects through the preparation of detailed reports and presentations that summarize experiment results.
- Identifies problems, investigates alternatives, and recommends possible courses of action.
- Maintains current knowledge of the diagnostics industry, including technological developments that may assist in delivering new processes, improved products, or entirely new products
- Prepares reports for submission to regulatory agencies such as the FDA.
- Prepares and/or contributes to articles for publication. Communicates and presents scientific/technical results at internal and external meetings.
- Supervises and serves as a mentor to technical staff
- Works closely with other teams to collaboratively resolve issues
- Performs miscellaneous job-related duties as assigne
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Application Development Scientist
| Job Description
The Application Development Scientist will be responsible for translating Spear Bio’s technology platform and applying it to customers and strategic partner applications. The role will have dual responsibilities being a member of the R&D team reporting to the Head of Application Development but also directly supporting the commercial team’s activities as directed by the Sr. Director of Business Development. As such, The Application Development Scientist will be expected to participate in product and work-flow development activities while also be expected to develop relationships with key customers and KOLs support their use of Spear Bio’s products and technology. The Application Development Scientist will be expected to be an expert on the product and how customers apply it.
| Requirements
Role-Specific Requirements
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- PhD in Biology, Biochemistry, Molecular Biology with extensive immunoassay experience
- 3-5 years’ academic or industry experience on assay or molecular biology technology development, field applications and/or diagnostics lab test management.
- In-depth knowledge in immunology, oncology or neurology is preferred
- General requirements
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- Strong analytical and problem-solving skills
- Ability to maintain sustained attention to details
- Excellent communication skills: interpersonal (verbal), writing, and via presentations
- Ability to convey information in a clear and concise manner
- Demonstrated ability to work collaboratively and in teams
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| Responsibilities
- Develops, plans, conducts and records results from complex experiments across product areas.
- Contributes ideas for new product development with a customer mind-set.
- Performs laboratory experiments following defined protocols and company procedures or innovates to develop new protocols for existing or new technologies.
- Develop platform protocols and translate them to commercial documents.
- Own external technical documentation including IFUs, product data sheets, and application note production and editing process.
- Support and enable the sales process and strategic partnering process by presenting to customers and strategic partners and educating them on our technology and platform.
- Own customer success in setting up assay workflow and providing scientific and technical support.
- Work with external partners, customers, and KOLs to develop new data & application notes, as well as new workflows and assay solutions for customers.
- Understand customer pain points and relay VOC back to the Marketing and Product Development teams.
- Be a thought leader in the field, maintaining current knowledge on competitors and key applications and represent Spear Bio at conferences, tradeshows, and academic lectures.
| Apply
Head of Product Management
| Job Description
The Head of Product Management will be responsible for the development and expansion of Spear Bio’s Product Portfolio to fulfill both Spear Bio’s mission and vision.
The role will report directly to the CEO and work closely with the R&D and Commercial Teams. The Role will be expected to drive product planning and product marketing decisions. This will include strategic planning and strategic marketing, as well as tradeoffs on product features and benefits and tactical launch decisions. The Head of Product Management will be expected to be a leader and expert on Spear Bio’s markets, customer needs, competitive offerings, and key points of product differentiation.
| Requirements
- Role-Specific Requirements
- 5-10 years of successful experience in product management, product planning, and product marketing in relevant fields, e.g., medical technology, diagnostics, or life sciences
- Relevant Bachelor’s or Master’s degree (e.g., Business, Marketing, Biology, Biochemistry…), MBA a plus
- Strong understanding of product marketing, product development process
- Strong track record at defining and launching products
- Knowledge in immunology, oncology, or neurology preferred
- General requirements
- Strong analytical and problem-solving skills
- Ability to maintain sustained attention to details
- Ability to grasp technical, clinical, and scientific information
- Business savvy and mindset
- Excellent communication skills: interpersonal (verbal), writing, and designing presentations
- Ability to convey information in a clear and concise manner
- Demonstrated ability to work collaboratively and in teams
- Ability to travel (up to 25%)
| Responsibilities
- Develop deep fact-based insights into market trends, customer needs, and competitive offerings
- Plan product portfolio with R&D based on customer & market priorities, and technical roadmap
- Define product marketing mix: STP & 4Ps, leveraging customer, competitive, and market insights
- Drive product definition with R&D team through features and benefits and tradeoffs (time/cost/risk)
- Drive product marketing execution within the new product development process
- Prepare and execute product launches in coordination with commercial team and the company
- Relay customer pain points and potential solutions as inputs to the new product development process
- Articulate market and customer insights as inputs to the product roadmaps and corporate strategy
- Maintain up-to-date knowledge on competitors, competitive products, and key applications
- Represent Spear Bio with KOLs, key customers and partners as relevant (incl. conferences & tradeshows)
| Apply
Bioconjugation Specialist
| Job Description
The Bioconjugation Specialist will be responsible for performing Spear Bio’s manufacturing activities and ensuring regulatory compliance. The role will have cross-functional responsibilities reporting to the Head of Product Development but also interfacing with commercial, finance, and lab facilities teams. The Bioconjugation Specialist will be expected to have demonstrated experience in conjugation chemistry and a good knowledge of GMP production for assay technologies.
| Requirements
Role-Specific Requirements
- B.S. or M.S. or higher in Chemistry, Biochemistry, or related degree or equivalent experience.
- 2-8 years of experience in the production, purification, and characterization of conjugate molecules on research scale and medium scale is preferred.
- Experiences with bioconjugates or drug delivery modalities such as targeted peptides, oligonucleotides, or antibody-drug conjugates (ADCs), including site-specific approaches.
- Hands-on experience preferably with peptide chemistry, antibody conjugation methods
- The ideal candidate for this position will have demonstratable knowledge and understanding of GMP, QA and QC functions associated with the manufacturing of immunoassay products and compliance with ISO 9001 or similar.
- Have direct experience with immunoassay method development and optimization, as well as data analysis.
- Detailed working history with lab equipment and knowledge of lab safety protocols.
General Requirements
- They must be able to work independently and have a strong understanding of the theory and the biology behind the application and the products.
- Excellent documentation, organization, communication, multi-tasking, and problem-solving skills.
- The successful candidate should possess strong presentational and interpersonal skills with the capability to establish collaborative working relationships within QA/QC, and with members of the Analytical Method Development, Manufacturing teams.
- The successful candidate must be prepared to work on-site in Woburn MA 100%.
| Responsibilities
- We are looking for a highly motivated person who loves science and wants to be part of a dynamic and fast paced team.
- The Bioconjugation Specialist will be responsible for management of manufacturing, and will be involved in developing, qualifying, and/or validating robust methods to support product release and characterization by collaborating with internal functions groups and external CDMOs.
- Synthesize bioconjugates using established chemistries.
- Contribute to the development of new bioconjugation methodologies.
- Purify bioconjugates by size exclusion chromatography, ion-exchange chromatography, affinity chromatography and hydrophobic interaction chromatography.
- Optimize protein and antibody conjugation and purification methods.
- Working knowledge of AKTA platform or equivalents.
- Characterize bioconjugates using multiple techniques such as UV/Vis, fluorescence, HPLC, MS and
- Serve as Subject Matter Expert for internal and external matters related to QA and QC.
- Analytical techniques include, but are not limited to, Real-Time PCR, immunoassays (immunoblotting and ELISAs), and gel-based assays (SDS-PAGE and CE-SDS).
- Participates in inspection readiness activities.
- Assist with equipment qualification and/or validation activities: drafting and executing IOQ protocols, drafting and reviewing reports and other documentation.
- Responsible for conducting and/or assisting with laboratory investigations: deviations, OOS/OOT, aberrant/unexpected results, and invalid results.
- Responsible for conducting and/or assisting with the identification, initiation, and closure of quality events (Deviations and CAPAs) related to analytical testing.
- Responsible for overseeing accurate, complete, and timely records (test records and laboratory notebooks), in compliance with ISO 13485. FDA 21 CFR 820 and 21 CFR Part 11, EU Medical Device Regulations 93/42/EEC, and EU MDR/2017 where applicable.
- Maintains familiarity with current technology-related information and/or literature and conducts project-related information searches and may be involved in extensive literature searches.
- Trains others in laboratory procedures and processes, and in the design, execution, and analysis of experiments. Provides feedback to supervisor on training progress.
- Performs other duties and assumes additional departmental responsibilities as required. Performs other assignments and tasks as directed.
- Demonstrates excellent written and verbal communication skills within and between departments. Maintains appropriate laboratory records, notebooks, and other formal company documentation, as required.
- Works on complex problems where analysis of situations or data requires an in-depth evaluation of various factors, and exercises judgment within broadly defined practices and policies to determine appropriate conclusions and follow-up action.
| Apply
Head of Application Development
| Job Description
The Head of Application Development will be responsible for developing and supporting the applications of Spear Bio’s technology with customers and strategic partners. The role will report directly to CTO and work closely with the Commercial Team. The Role will be expected to participate in product and workflow development activities as well as relationships with key customers, key opinion leaders, and strategic partners. The Head of Application Development will be expected to be a leader and expert on the platform and its applications.
| Requirements
Role-Specific Requirements
- Ph.D. in Biology, Biochemistry, or Molecular Biology with extensive immunoassay experience or similarly relevant BS/MS with >10 years’ progressive industry experience in assay or molecular biology technology development, field applications, and/or diagnostics lab test management and team leadership.
- Strong network in drug development and contract research world.
- Strong understanding of immunoassay technologies, methods, and strategies.
- In-depth knowledge of immunology, oncology, or neurology preferred.
-
General Requirements
- Strong analytical and problem-solving skills.
- Ability to maintain sustained attention to details.
- Excellent communication skills: interpersonal (verbal), writing, and designing presentations.
- Ability to convey information in a clear and concise manner.
- Demonstrated ability to work collaboratively and in teams.
- Ability to travel (up to 25%).
| Responsibilities
- Lead application development and field application functions.
- Develops, plans, conducts, and records results from complex experiments across product areas.
- Performs laboratory experiments following defined protocols and company procedures or innovates to develop new protocols for existing or new technologies.
- Provide product management and new product development inputs from a customer standpoint.
- Relay customer pain points and potential solutions as inputs of the new product development process.
- Articulate inputs to the product roadmaps and corporate strategy with Leadership Team.
- Develop technical customer content with inputs from internal and external partners: new data & application notes, new workflows, and assay solutions.
- Develop platform protocols and translate them into commercial documents.
- Lead the development and creation of external technical documentation, including IFUs, product data sheets, and application note production and editing process.
- Own customer technical success by providing scientific, technical, and product training and support.
- Support the sales and strategic partnerships processes by conducting presentations on our technology and platform to customers and partners
- Maintain up-to-date knowledge of competitors and key applications.
- Represent Spear Bio at conferences, tradeshows, and academic lectures.
| Apply
Scientist/Senior Scientist, Nucleic Acid and Protein Chemistry
| Job Description
The Scientist/Senior Scientist, Nucleic Acid and Protein Chemistry will be responsible for performing Spear Bio’s manufacturing activities and ensuring regulatory compliance. The role will have cross-functional responsibilities reporting to the Head of Product Development but also interfacing with commercial, finance and lab facilities teams. The Scientist/Senior Scientist, Nucleic Acid and Protein Chemistry will be expected to have demonstrated experience in conjugation chemistry and the good knowledge of GMP production for assay technologies.
| Requirements
Role-Specific Requirements
- B.S./M.S. or Ph.D. in Chemistry, Biochemistry, or related degree or equivalent experience.
- 2-8 years of experience in the production, purification, and characterization of conjugate molecules on research scale and medium scale is preferred.
- Experience with synthesis of bioconjugates or drug delivery modalities such as targeted peptides, oligonucleotides, or antibody-drug conjugates (ADCs), including site-specific approaches.
- The ideal candidate for this position will have demonstrable knowledge and understanding of GMP, QA and QC functions associated with the manufacturing of immunoassay products and compliance with ISO 9001 or similar.
- Have direct experience with immunoassay method development and optimization, as well as data analysis.
- Detailed working history with lab equipment and knowledge of lab safety protocols.
-
General Requirements
- They must be able to work independently and have a strong understanding of the theory and the biology behind the application and the products.
- Excellent documentation, organization, communication, multi-tasking, and problem-solving skills.
- The successful candidate should possess strong presentational and interpersonal skills with the capability to establish collaborative working relationships within QA/QC and with members of the Analytical Method Development, Manufacturing teams.
- Ability to work on complex problems where analysis of situations or data requires an in-depth evaluation of various factors and exercises judgment within broadly defined practices and policies to determine appropriate conclusions and follow-up action.
- The successful candidate must be prepared to work on-site in Woburn, MA 100%.
| Responsibilities
- Management of key analytical reagents, and will be involved in developing, qualifying, and/or validating robust methods to support product release and characterization by collaborating with internal functions groups and external CDMOs.
- Synthesize bioconjugates using established chemistries. Optimize protein and antibody conjugation and purification methods.
- Contribute to new method development for bioconjugates.
- Purify bioconjugates by size exclusion chromatography, ion-exchange chromatography, affinity chromatography, and hydrophobic interaction chromatography.
- Working knowledge of AKTA platform or equivalents.
- Characterize bioconjugates using multiple techniques such as UV/Vis, fluorescence, HPLC, MS and
- Analytical techniques include but are not limited to Real-Time PCR, immunoassays (immunoblotting and ELISAs), and gel-based assays (SDS-PAGE and CE-SDS).
- Responsible for overseeing accurate, complete, and timely records (test records and laboratory notebooks) in compliance with ISO 13485. FDA 21CFR 820 and 21 CFR Part 11, EU Medical Device Regulations 93/42/EEC, and EU MDR/2017 where applicable.
- Maintains familiarity with current technology-related information and/or literature and conducts project-related information searches and may be involved in extensive literature searches.
- Trains others in laboratory procedures and processes and in the design, execution, and analysis of experiments. Provides feedback to supervisor on training progress.
| Apply